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This page gives you access to all the studies carried out by French researchers, identified on Covid-19.

To view other resources related to Covid-19, click here.


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Métadonnées
Identification
General Aspects
Scientific investigator(s) (Contact)
Collaborations
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Covid-19 : 82 forms

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COVI-ST - Longitudinal follow-up of the risk of exhaustion, anxiety and quality of life of hospital staff in the context of the COVID-19 pandemic

Head : Guinot Isabelle

Version 1
Overview

19

Last update : 05/05/2021

COVI-ST - Longitudinal follow-up of the risk of exhaustion, anxiety and quality of life of hospital staff in the context of the COVID-19 pandemic

Head : Guinot Isabelle

Main objective

Evaluate the impact of the COVID-19 pandemic on burn-out 2 years after the "CHMS Emergency Response Plan (Plan Blanc)", i.e. as of 06/07/2022

Inclusion criteria

Volunteer hospital staff, having worked at CHMS during the Emergency Response Plan for the COVID-19 pandemic, i.e. from 17/03/2020 to 05/07/2020
- Aged >18 years,
- Not under legal protective measures
- Professional having given free, informed confirmation of their non-objection to
taking part in the study

COVITREM-1 - Prognostic value of measuring the activation pathway for Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) in patients hospitalised due to COVID-19

Head : GIBOT Sébastien

Version 1
Overview

20

Last update : 05/06/2021

COVITREM-1 - Prognostic value of measuring the activation pathway for Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) in patients hospitalised due to COVID-19

Head : GIBOT Sébastien

Main objective

Evaluate the prognostic value of initial TREM-1 activation (first measurement collected) on clinical deterioration in patients hospitalised due to COVID-19 in medical, emergency and intensive care departments

Inclusion criteria

Patients aged over 18 years
Hospitalised for less than 3 days for any reason whatsoever, but screened for Covid-19. SARS-CoV-2 infection should be "probable" or "confirmed" according to the definition published on 3 April by Santé Publique France (French Public Health Agency): laboratory confirmation (by positive RT-PCR further to nasopharyngeal sample or any other sample and/or positive serology indicating infection) or by a composite endpoint combining characteristic pulmonary impairment upon imaging and clinical/laboratory effects suggesting viral infection (including: fever, cough, chest pain, and biological inflammatory syndrome, lymphopenia, elevated liver enzymes).
Registered with a social security scheme or a beneficiary of such a scheme
The patient or their representative will have received information on the study and signed the emergency informed consent/inclusion form in compliance with Article L.1122-1-3 of the French Public Health Code (CSP)

EDIFICE - Observational study on the diagnostic evaluation of the intestinal microbiota of French people infected with the Coronavirus

Head : MARTI Guy

Version 1
Overview

21

Last update : 05/05/2021

EDIFICE - Observational study on the diagnostic evaluation of the intestinal microbiota of French people infected with the Coronavirus

Head : MARTI Guy

Main objective

Validate the hypothesis for a relationship between the loss of diversity of the intestinal microbiota and screening positive for COVID-19, by comparing hospitalised COVID-19 positive patients with an exposed French population represented by hospital medical and paramedical personnel

Inclusion criteria

COVID-19 positive patients: hospitalised patients diagnosed with COVID-19 in one of the two investigating sites, and able to provide a stool sample
Exposed subjects: Medical and paramedical personnel working at one of the two investigating sites, having been in direct contact with the patients.
Aged between 18 and 85 years
Subjects able to read the French-language study information leaflet
Patients with social cover

FILO-COVIM - Observational study on the impact of the COVID-19 epidemic on patients with myeloproliferative neoplasms

Head : KILADJIAN Jean-Jacques, CIC 1427

Version 1
Overview

22

Last update : 04/20/2021

FILO-COVIM - Observational study on the impact of the COVID-19 epidemic on patients with myeloproliferative neoplasms

Head : KILADJIAN Jean-Jacques, CIC 1427

Main objective

Describe the rate of serious Coronavirus infections in the different subgroups of patients with myeloproliferative neoplasms defined by ongoing treatment during the epidemic.

Inclusion criteria

Male or female aged 18 years and over
Male or female patient with PV, ET, PMF or MF secondary to PV or ET diagnosed before the
COVID-19 pandemic
Attending an appointment from April 2020

HOME-CoV - Hospitalization or Outpatient ManagEment of patients with a proven or probable SARS-CoV-2 infection

Head : DOUILLET Delphine

Version 1
Overview

23

Last update : 02/03/2021

HOME-CoV - Hospitalization or Outpatient ManagEment of patients with a proven or probable SARS-CoV-2 infection

Head : DOUILLET Delphine

Main objective

the composite rate of adverse outcomes [ Time Frame: day 7 ]
Adverse outcomes include intubation with mechanical ventilation requirement and death (Stage ≥ 6 on "Ordinal Scale for Clinical Improvement" of the World Health Organization) within 7 days after inclusion.

Inclusion criteria

The rate of hospitalization [ Time Frame: 24 hours ]
The rate of patients hospitalized after admission to the emergency room including patients discharged home more than 24 hours after admission.

It will be analyzed in a hierarchical approach, only if first primary objective is positive i.e. non-inferiority of HOME-CoV strategy versus current practice on the rate of adverse outcomes.

LICORNE - Predictive factors for mortality at D28 for patients managed at Lille University Hospital for COVID-19

Head : CHOPIN Marie Charlotte
DEPLANQUE Dominique

Version 1
Overview

24

Last update : 05/05/2021

LICORNE - Predictive factors for mortality at D28 for patients managed at Lille University Hospital for COVID-19

Head : CHOPIN Marie Charlotte
DEPLANQUE Dominique

Main objective

The primary objective of this study is to identify the predictive factors for mortality at D28 of SARS-CoV-2 infection in patients managed for COVID-19 at Lille University Hospital, via the creation of an epidemiological, clinical, biological, immunological, genetic, microbiological, pathological, radiological and therapeutic database, indicating the results of functional tests.
NB: The analysis will exclude patients who are "confirmed cases" with serious SARS-CoV-2 infection managed in a conventional medicine department owing to the therapeutic limitations (TL) which existed prior to SARS-CoV-2 infection, due to incurable disease or underlying comorbidities.

Inclusion criteria

Any adult patient, "suspect patients", "possible cases", "probable cases" or "confirmed cases" of SARS-CoV-2 infection admitted to Lille University Hospital.

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